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THE WBF BOOK SERIES--ISA 88 and ISA 95 in the Life Science Industries by The WBF

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CHAPTER 13

The Road to Full MES Integration: Practical Experience from the Pharmaceutical Industry
Presented at the WBF North American Conference, March 5–8, 2006, by
Niels Andersen, M Sc (Physics)Automation Specialistnca@nne.dkNNE A/S, Gladsaxevej 363, DK-2860 Soeborg, Denmark

Abstract

This chapter describes the successful implementation of a Manufacturing Execution System (MES) on top of a Process Control System (PCS) in the world’s largest insulin Active Pharmaceutical Ingredient (API) plant, operating with more than 300 units with more than 500 recipes and 600,000 parameters. The functionality of the actual MES database application is described, along with its evolution from early versions in finished-goods production to a modular ...

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