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The Cure in the Code by Peter Huber

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10

ADAPTIVE TRIALS

AS DISCUSSED IN Chapter 9, a recent NRC report concludes that working out the etiology of complex diseases will require the analysis of “biological and other relevant clinical data derived from large and ethnically diverse populations” in a dynamic, learn-as-you-go collaboration among biochemists, clinical specialists, patients, and others. As it happens, good drug science requires much the same—a drug is just one more molecule added to the molecular ecosystem that constitutes a body. The NRC report assumes as much when it recommends that doctors be allowed to consult the proposed Knowledge Network to find out how other patients have fared when already licensed drugs are prescribed outside the FDA-approved boundaries. As that ...

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