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Success Probability Estimation with Applications to Clinical Trials by Daniele De Martini

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TOPIC INDEX

A

adaptation

alternative hypothesis

of clinical equivalence

of clinical non-inferiority

of clinical superiority

of inequality

of superiority

asterisk scale

two-tailed test

average power

B

bootstrap

lower bound for SP

estimator of SP

replications

technique

C

calibration

chance

chi-square test

2 × C tables

clinical trials

cost

failure

rate of

times

confidence interval

for noncentrality parameter

for the effect size

one-sided

for RP

two-sided

confidence level

conservativeness

amount of

optimal amount of

estimation

nonparametric

cost

clinical trials

critical value

D

disagreement

in WRS RP-testing

distribution function

empirical

corrected

smoothed

E

effect size

γ-lower bound

assumed

different in phase II

estimate

estimator

conservative

distribution of

generic

pointwise

generic

nonparametric

of clinical relevance

true

estimate

estimation

conservative

pointwise

estimator

conservative

consistent

pointwise

experiment

ideal

large

pilot

experimental

planning

proof

G

Gaussian distribution

standard

H

Hodges-Lehmann estimator

L

launching

criteria

different phase II effect size

equivalence of

criterion

of clinical relevance

of maximum sample size

of phase II statistical

significance

probability

launching criteria for

chi-square test

2 × C tables

Mantel-Haenszel

log-rank test

parametric model

t-test

equal variances

unequal variances

two proportions test

WRS test

link function

chi-square test

2 × C tables

Mantel-Haenszel

log-rank test

t-test

equal variances

unequal variances

two proportions ...

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