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Recent Advances in Drug Delivery Technology

Book Description

Technological innovations have become the impetus for continuous developments in medical research. With the assistance of new technologies, effective drug delivery techniques have been improved for optimal patient care. Recent Advances in Drug Delivery Technology is a pivotal reference source for the latest scholarly research on the application of pharmaceutical technology to optimize techniques for drug delivery in patients. Focusing on novel approaches in pharmaceutical science, this book is ideally designed for medical practitioners, upper-level students, scientists, and researchers.

Table of Contents

  1. Cover
  2. Title Page
  3. Copyright Page
  4. Book Series
    1. Mission
    2. Coverage
  5. Editorial Advisory Board and List of Reviewers
    1. Editorial Advisory Board
  6. Preface
    1. CHAPTER COMPOSITION
  7. Section 1: Nanomedicine
    1. Chapter 1: Personalized Approach in Nanomedicine
      1. ABSTRACT
      2. INTRODUCTION
      3. BACKGROUND
      4. ADVERSE EFFECTS AND RISK ASSESSMENT OF NANOFORMULATIONS
      5. EFFECT OF NPS PROPERTIES ON COMPOSITION OF PROTEIN CORONA
      6. SOLUTIONS AND RECOMMENDATIONS
      7. FUTURE RESEARCH DIRECTIONS
      8. CONCLUSION
      9. REFERENCES
      10. KEY TERMS AND DEFINITIONS
  8. Section 2: Pharmacogenetics
    1. Chapter 2: Drug Delivery Strategies for Tolerogenic Therapy for Autoimmune Diseases in an Antigen-Specific Manner
      1. ABSTRACT
      2. INTRODUCTION
      3. BACKGROUND OF DRUG DELIVERY VEHICLES
      4. NANO/MICROPARTICLES FOR THE TREATMENT OF AUTOIMMUNITY
      5. FUTURE CHALLENGES AND RECOMMENDATIONS
      6. CONCLUSION
      7. REFERENCES
    2. Chapter 3: Cancer Drug Delivery
      1. ABSTRACT
      2. INTRODUCTION
      3. SOMATIC PHARMACOGENETIC BIOMARKERS
      4. GERM-LINE PHARMACOGENETIC BIOMARKERS
      5. SUPPORTIVE CARE PHARMACOGENETIC BIOMARKERS
      6. FUTURE RESEARCH DIRECTIONS
      7. CONCLUSION
      8. REFERENCES
      9. ENDNOTE
      10. APPENDIX
  9. Section 3: Proteomics and Genomics
    1. Chapter 4: Genomics and Proteomic Approach in the Treatment of Various Human Diseases
      1. ABSTRACT
      2. CONCLUSION
      3. ACKNOWLEDGMENT
      4. REFERENCES
  10. Section 4: Bioinformatics
    1. Chapter 5: Bioinformatics and Its Therapeutic Applications
      1. ABSTRACT
      2. INTRODUCTION
      3. WHAT IS BIO-INFORMATICS
      4. CONVERSION OF 2D TO 3D
      5. DOCKING TOOL
      6. ORGANISM INFORMATION BIOINFORMATICS DATA
      7. MOLECULE INFORMATION BIOINFORMATICS DATA
      8. ACCOMPLISHMENTS OF BIOINFORMATICS
      9. THERAPEUTIC APPLICATION
      10. BIOINFORMATICS USED IN DATA MINING
      11. BIOINFORMATICS AND DRUG DISCOVERY
      12. BRIEF HISTORY OF COMPUTER AIDED DRUG DESIGN
      13. COMPUTER AIDED DRUG DESIGN
      14. BIOINFORMATICS AND MEDICAL SCIENCES (CLINICAL SCIENCES)
      15. GENE THERAPY
      16. MICROBIAL GENOME APPLICATION
      17. MOLECULAR MEDICINE
      18. PERSONALIZED MEDICINE
      19. BIOINFORMATICS IN AGRICULTURE
      20. FUTURE RESEARCH DIRECTIONS
      21. CONCLUSION
      22. REFERENCES
      23. KEY TERMS AND DEFINITIONS
  11. Section 5: Nutraceuticals and Phytopharmaceuticals
    1. Chapter 6: An Overview and Therapeutic Applications of Nutraceutical and Functional Foods
      1. ABSTRACT
      2. INTRODUCTION
      3. NUTRACEUTICAL CONCEPTS
      4. COMPARISON BETWEEN FUNCTIONAL FOODS, MEDICAL FOODS AND DRUGS
      5. PROTEIN, PEPTIDE, AND AMINO ACIDS AS NUTRACEUTICAL
      6. CARBOHYDRATE, GLYCOSIDE, AND FIBER AS NUTRACEUTICAL AND FUNCTIONAL FOODS
      7. LIPID AND FATTY ACIDS AS NUTRACEUTICAL AND FUNCTIONAL FOODS
      8. MUSHROOM AS NUTRACEUTICAL AND FUNCTIONAL FOODS
      9. VITAMINS AS NUTRACEUTICAL AND FUNCTIONAL FOODS
      10. PHYTOCHEMICAL (FLAVONOIDS) AS NUTRACEUTICAL AND FUNCTIONAL FOODS
      11. MINERALS AND TRACE ELEMENTS USED AS NUTRACEUTICAL AND FUNCTIONAL FOODS
      12. REAGENTS DERIVED FROM OTHER SOURCES
      13. MARKETED PRODUCTS OF NUTRACEUTICAL AND FUNCTIONAL FOODS
      14. SUPPLIERS OF NUTRACEUTICAL AND FUNCTIONAL FOODS
      15. APPLICATION OF NUTRACEUTICAL AND FUNCTIONAL FOODS IN HEALTH BENEFITS AND PREVENTION OF DISEASES
      16. CONCLUSION
      17. CONFLICT OF INTEREST
      18. REFERENCES
    2. Chapter 7: Phytoparmaceuticals and Its Applications in Therapy
      1. ABSTRACT
      2. CONCEPTS
      3. HISTORY
      4. PHYTOPHARMACEUTICAL PRODUCTION
      5. PHYTOPHARMACEUTICAL FORMS
      6. QUALITY CONTROL
      7. CLINICAL TRIALS
      8. CONCLUSION
      9. REFERENCES
    3. Chapter 8: A Perspective on the Phytopharmaceuticals Responsible for the Therapeutic Applications
      1. ABSTRACT
      2. INTRODUCTION
      3. BACKGROUND
      4. MAIN FOCUS OF THE CHAPTER
      5. ISSUES, CONTROVERSIES, PROBLEMS
      6. NOTE
      7. REFERENCES
    4. Chapter 9: Phytopharmaceutical Applications of Nutraceutical and Functional Foods
      1. ABSTRACT
      2. INTRODUCTION
      3. NUTRACEUTICALS: THEN AND NOW
      4. FUNCTIONAL FOODS AS NATURAL HEALTH PRODUCTS
      5. PHYTOPHARMACEUTICALS OF NUTRACEUTICAL IMPORTANCE
      6. ROLE OF PHYTOPHARMACEUTICALS IN HEALTH AND DISEASES
      7. CONCLUSION
      8. ACKNOWLEDGMENT
      9. REFERENCES
      10. ADDITIONAL READING
  12. Section 6: Cosmeceuticals
    1. Chapter 10: Cosmeceuticals
      1. ABSTRACT
      2. INTRODUCTION
      3. BACKGROUND
      4. REGULATION, REVIEW, SAFETY, AND EFFICACY OF COSMECEUTICALS INGREDIENTS
      5. SKIN WHITENING AND DEPIGMENTING COSMECEUTICALS
      6. ANTIAGING COSMECEUTICALS
      7. SUNSCREENS COSMECEUTICALS
      8. HAIR LOSS AND HAIR CARE COSMECEUTICALS
      9. SOLUTIONS AND RECOMMENDATIONS
      10. FUTURE RESEARCH DIRECTIONS
      11. CONCLUSION
      12. REFERENCES
      13. KEY TERMS AND DEFINITIONS
    2. Chapter 11: Cosmeceuticals
      1. ABSTRACT
      2. MILK COSMECEUTICALS: A NOVEL APPROACH FOR EXTERNAL DRUG DELIVERY
      3. HUMAN SKIN
      4. FRAGRANCES OF COSMETICS
      5. MILK
      6. VITAMINS
      7. ELECTROLYTES
      8. SODIUM
      9. SKIN BEAUTY (COSMETIC) ACTIVITY
      10. BLOOD FLOW TO SKIN
      11. CLINICAL VIGNETTES
      12. REGIMENS FOR TREATMENTS
      13. PSORIASIS
      14. DANDRUFF
      15. EYE INFECTIONS
      16. HERPES
      17. CONJUNCTIVITIS
      18. VITILIGO
      19. BODY MASSAGES: FEELING BEAUTY
      20. VARIOUS TYPES OF MASSAGE
      21. ADDITIONS TO CAMEL MILK TO MAKE COSMECEUTICALS
      22. ANTIWRINKLE MOISTURIZING CREAMS
      23. EYE-CREAM
      24. SORES ABRASIONS
      25. GENITAL TRACT PROBLEMS
      26. BOYS' GENITAL PROBLEMS
      27. DANDRUFF
      28. ACNE
      29. ACNE SCARS /SCARS IN GENERAL
      30. ATOPIC DERMATITIS
      31. LOCALIZED PSORIASIS
      32. TOES: TINEA PEDIS
      33. BREASTS
      34. STEROIDS
      35. SKIN ANTIBODIES
      36. METHODS OF ADMINISTRATION OF CAMEL-MILK COSMECEUTICALS
      37. OTHER MAMMALIAN MILK USED AS COSMECEUTICALS
      38. EQUINE MILK COSMECEUTICALS
      39. CONCLUSION
      40. REFERENCES
  13. Section 7: Red Blood Cells
    1. Chapter 12: Resealed Erythrocytes as Drug Carriers and Its Therapeutic Applications
      1. ABSTRACT
      2. INTRODUCTION
      3. BLOOD
      4. RESEALED ERYTHROCYTES
      5. PREPARATIVE METHODOLOGY
      6. IN VITRO CHARACTERIZATION OF RESEALED ERYTHROCYTES
      7. ADVANTAGE OF RESEALED ERYTHROCYTES (GOTHOSKAR, 2004)
      8. APPLICATIONS OF RESEALED ERYTHROCYTES
      9. CURRENT NOVEL APPROACHES
      10. IN VITRO STORAGE OF RESEALED ERYTHROCYTES
      11. CONCLUSION
      12. CONFLICT OF INTEREST
      13. ACKNOWLEDGMENT
      14. REFERENCES
  14. Section 8: Herbals
    1. Chapter 13: New Herbal Approaches for the Treatment of Diabetic Kidney Diseases and Its Therapeutic Implications
      1. ABSTRACT
      2. INTRODUCTION
      3. EPIDEMIOLOGY
      4. RISK FACTORS IN DKDs
      5. STAGES IN DIABETIC KIDNEY DISEASES
      6. PATHOLOGY AND PATHOPHYSIOLOGY OF DIABETIC KIDNEY DISEASES
      7. HEMODYNAMIC PATHWAY
      8. METABOLIC PATHWAY
      9. THE POLYOL PATHWAY
      10. HEXOSAMINE PATHWAY
      11. ADVANCED GLYCATION END PRODUCTS (AGEs)
      12. THE PKC PATHWAY
      13. GROWTH FACTORS AND CYTOKINES
      14. CELL SIGNALING AND TRANSCRIPTION FACTORS
      15. ROLE OF INFLAMMATION
      16. ALTERNATIVE PATHWAYS OF DKD
      17. HISTOPATHOLOGICAL CHANGES IN CHRONIC KIDNEY DISEASES
      18. CLASS I: THICKENING OF THE GLOMERULAR BASEMENT MEMBRANE OR PREDIABETIC LESIONS
      19. CLASS II: MESANGIAL EXPANSION, MILD (iia) OR SEVERE (iib)
      20. CLASS III: NODULAR SCLEROSIS (KIMMMELSTEIL-WILSON LESIONS)
      21. CLASS IV: ADVANCED DIABETIC GLOMERULOSCLEROSIS
      22. THE FILTRATION BARRIER: A MULTICOMPONENT APPARATUS
      23. ENDOCRINOLOGICAL SIGNIFICANCE
      24. TREATMENT MODALITIES IN MODERN MEDICINE
      25. DRUGS MECHANISM OF ACTION
      26. MARKERS OF THE CHRONIC DIABETIC RENAL FAILURE
      27. HS-CRP (HIGH SENSITIVITY CRP) AND CRP (C - REACTIVE PROTEIN)
      28. IL-18 (INTERLEUKIN-18)
      29. TIMP-β 1(TISSUE INHIBITOR OF METALLOPROTEINASES-β 1)
      30. PTX3 (PENTRAXIN-3)
      31. TGF-β1 (TRANSFORMING GROWTH FACTOR-β1)
      32. TBARS (THIOBARBITURIC REACTIVE SUBSTANCES) AND MDA (MALONDIALDEHYDE)
      33. PROTEIN CARBONYL
      34. AGEs (ADVANCED GLYCATION END PRODUCTS)
      35. URINARY 8-HYDROXY GUANOSINE 4 HYDROXY NONENAL
      36. ANTIOXIDANT ENZYMES (SUPEROXIDE DISMUTASE, CATALASE AND GLUTATHIONE PEROXIDASE)
      37. ADMA (ASSYMETRIC DIMETHYLARGININE)
      38. PROTEIN REDUCED THIOLS
      39. β-TRACE PROTEIN (BTP)
      40. CYSTATIN C (CYSTATIN 3)
      41. PODOCIN
      42. NEPHRIN
      43. PODOCALYXIN
      44. NGAL (NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN)/ LIPOCALIN-2 (LCN2)/ ONCOGENE 24p3
      45. KIM-1(KIDNEY INJURY MOLECULE-1)
      46. NAG (N-ACETYL β-GLUCOSAMINIDASE)
      47. L-FABT (LIVER TYPE FATTY ACIDS BINDING PROTEIN)
      48. HERBAL APPROACHES TO DIABETIC KIDNEY DISEASES
      49. ROUTES OF HERBAL DRUG ADMINISTRATION
      50. CONCLUSION
      51. REFERENCES
      52. KEY TERMS AND DEFINITIONS
      53. APPENDIX: ABBREVIATIONS
  15. Compilation of References
  16. About the Contributors