For the most part, a simple filesystem-level backup of your buildout folder (that it, is the one housing
buildout.cfg) is all that's necessary. Your add-on products,
buildout.cfg, Zope and ZEO instances, log files—all are conveniently centralized in that folder, so including it in your normal backup routine will almost completely suffice. What remains is to ensure a reliable backup of the ZODB: like many databases, it requires some special care to copy it while it is running.
Of course, it would be possible to shut down ZEO, copy the
Data.fs to a backup medium, and then start everything back up again, but your site would be unavailable while you did it.
repozo, a tool included in your ...