6.4. Power Determination in a Purely Nonparametric Sense

The title of this section must seem a bit of an enigma. What does the expression "in a purely nonparametric sense" really mean? Let's begin by reviewing some basic concepts in experimental design and power in the familiar parametric sense. We will then demonstrate a nonparametric approach to the same setting. Lastly, we will compare and contrast the two approaches to highlight important features.

Consider the design of a simple two-group experiment. Subjects or samples are randomized to one of two groups and receive a treatment. After treatment, a measurement is collected and the investigators wish to see if evidence exists to declare the responses of the two groups to be "different". ...

Get Pharmaceutical Statistics Using SAS now with the O’Reilly learning platform.

O’Reilly members experience books, live events, courses curated by job role, and more from O’Reilly and nearly 200 top publishers.