6.1. Introduction
Why are nonparametric statistical methods important to pharmaceutical research? To really address this question, we first must begin by looking at the nature of pharmaceutical research. The goal of pharmaceutical research is to discover and develop new medicines that are able to cure or moderate various disease symptoms or conditions. The disease response (i.e., physiological trauma) can vary greatly from individual to individual because of a complex inherent genetic variability. The corresponding statistical phenomenon associated with this genetic variation to disease response is that measurements collected on such a cohort can be skewed by the extreme response of a small portion of the individuals under consideration.
Consider, ...
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