Pharmaceutical Analysis

Introduction

The regents are mainly used for quantitative and qualitative analyses. There are number of reagents which are mainly used for the determination of pharmaceuticals. The most commonly employed reagents for the determinations are the following:

• 3-Methyl-benzathiazolinone hydrazone which is commonly known as MBTH. The colour production is bowed upon the oxidative coupling of this reagent with phenols, amines, carbonyl compounds, etc.
• Triketohydrindine hydrate commonly known as ninhydrin reagent. The basic principle involved in this is oxidative deamination of amino acids followed by reduction of ninhydrin to hydrindantin.
• Paradimethyl amino benzaldhyde (PDAB) (or) cinnamaldhyde (PDAC) condenses with amines in acidic media to product ...