Chapter 2
Analysis of Antimalarials
DEFINITION
Antimalarials are the agents which are used for the treatment of malaria.
Chemical classifcation of antimalarials:
- Cinchona alkaloids.
Example: Quinine, quinidine, cinchonine.
- 7-Chloro-4-amino quinolines.
Example: Chloroquine, amodiaquine.
- 9-Amino acridines.
Example: Acridine, aciquine.
- 8-Amino quinolines.
Example: Primaquine, pentaquine.
- 5-Antifolates.
Example: Nitroguanil, pyrimethamine.
- Sulphonamides.
Example: Sulphodoxine, sulphadiazine.
- Sulphones.
Example: Dapsone.
- Dihydrotriazines.
Example: Cycloguanil.
- Tetracyclines.
Example: Chlortertracycline.
- Anti-fungal agents.
Example: Ketaconazole, mecanazole.
- Oxidant drugs.
Example: Sesiqueterpeneoxides or ketones.
Analytical methods available for ...
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