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PACS and Imaging Informatics: Basic Principles and Applications, Second Edition by H. K. Huang, D.Sc., FRCR, FAIMBE

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CHAPTER 25

Computer-Aided Diagnosis (CAD) and Image-Guided Decision Support

Chapters 25 and 26 cover computer-aided detection and diagnosis. Chapter 25 discuses computer-aided diagnosis (CAD) and image-guided decision support with examples. Chapter 26 focuses on the integration of CAD with PACS for daily clinical use. In these two chapters, we use the terms aided, assisted, and guided loosely, but detection to only mean detect, and diagnosis to mean detection followed by diagnosis. For convenience, Figure 20.9 is reproduced here as Figure 25.1 showing how these two chapters (in orange purple color) correspond to other chapters in the domain of image informatics research.

25.1 COMPUTER-AIDED DIAGNOSIS (CAD)

25.1.1 CAD Overview

Computer-aided detection (CADe) and computer-aided diagnosis (CADx), or just in general, computer-aided diagnosis (CAD), research started in the early 1980s and has gradually evolved as a clinically supported tool. In mammography, CAD has in fact become a part of the routine clinical operation for detection of breast cancers in many medical centers and screening sites in the United States. In addition various CAD schemes are being developed for detection and classification of many different kinds of lesions obtained with the use of various imaging modalities because the concept of CAD is broad, and also for assisting radiologists by providing the computer output as a “second opinion.” The usefulness and practicality of CAD, however, depend on many factors, ...

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