Drug Delivery
People are very large compared to molecules, and it is important for therapeutic effectiveness that the drug molecules find the places in the body where they will be effective—antidepressants should be in the brain; anti-inflammatories at sites of stress; and anticancer drugs at the tumor sites. Bioavailability refers to the presence of drug molecules where they are needed in the body and where they will do the most good. The issue of drug delivery centers on maximizing bioavailability both over a period of time and at specific places in the body. In fact, over $65 billion of current pharmaceuticals suffer from poor bioavailability.
Increasing bioavailability is seldom as simple as increasing the amount of a drug that is used. In ...
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