The submission settings determine how Moodle behaves while the student is submitting their work:
The setting for Require students click submit button determines whether the student must submit the assignment all at once or if the student can save their submission as a draft and submit it later. If you select Yes for this setting, when the student is creating a submission, Moodle will display a Save button. After the student saves the submission, when the student enters the assignment, they will have the option to either edit what was saved or submit it.
The setting for Require that students accept the submission statement ...