Chapter 29

Antiviral Agents

LEARNING OBJECTIVES

  • Define HIV and AIDS with a view on the HIV life cycle

  • Describe the potential drug targets in the HIV life cycle

  • Categorize anti-HIV drugs based on the stage of intervention in the replicative cycle

  • Discuss the classes of reverse transcriptase inhibitors and compare nucleoside and non-nucleoside inhibitors

  • Describe the mode of action of each class of anti-HIV drugs

  • Define protease inhibitors and their importance

  • Define anti-HSV drugs and their utility

  • List some miscellaneous classes of antivirals

  • Describe the newer antiviral drugs

In the past few years, the antiviral chemotherapy area has witnessed a remarkable turnover of antiviral compounds, particularly in the domain of nucleoside analogues. ...

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