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MATLAB for Neuroscientists, 2nd Edition by Nicholas G. Hatsopoulos, Adam Seth Dickey, Tanya I. Baker, Marc D. Benayoun, Michael E. Lusignan, Pascal Wallisch

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Chapter 25

Voltage-Gated Ion Channels

Pascal Wallisch

This chapter will explore the dynamics of ion channels using methods similar to those introduced by Hodgkin and Huxley in 1952. You will derive ordinary differential equations that approximate real ion channel behavior and solve these equations using a numerical integrator written in the MATLAB® software. Finally, you will visualize the dynamics by predicting current responses to single channel voltage-clamp experiments.

Keywords

ion channels; gating variables; ligand gated; voltage gated; Runge-Kutta method

25.1 Goal of This Chapter

This chapter will explore the dynamics of ion channels using methods similar to those introduced by Hodgkin and Huxley in 1952. You will derive ordinary differential ...

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