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Materiomics

Book Description

This complete, yet concise, guide introduces you to the rapidly developing field of high throughput screening of biomaterials: materiomics. Bringing together the key concepts and methodologies used to determine biomaterial properties, you will understand the adaptation and application of materomics in areas such as rapid prototyping, lithography and combinatorial chemistry. Each chapter is written by internationally renowned experts, and includes tutorial paragraphs on topics such as biomaterial-banking, imaging, assay development, translational aspects, and informatics. Case studies of state-of-the-art experiments provide illustrative examples, whilst lists of key publications allow you to easily read up on the most relevant background material. Whether you are a professional scientist in industry, a student or a researcher, this book is not to be missed if you are interested in the latest developments in biomaterials research.

Table of Contents

  1. Coverpage
  2. Materiomics
  3. Title page
  4. Copyright page
  5. Contents
  6. List of contributors
  7. Preface
  8. Chapter 1 Introducing materiomics
    1. 1.1 Introduction to materiomics
    2. 1.2 The challenge of ‘living’ materials science
    3. 1.3 Dealing with complexity
    4. 1.4 Emergence of materiomics
    5. 1.5 Conclusion and book outline
  9. Chapter 2 Physico-chemical material properties and analysis techniques relevant in high-throughput biomaterials research
    1. 2.1 Basic principles: physical and chemical properties of polymeric biomaterials
    2. 2.2 Relation to materiomics: techniques that allow high-throughput material characterization
    3. 2.3 Future perspectives
    4. 2.4 Snapshot summary
  10. Chapter 3 Materiomics using synthetic materials: metals, cements, covalent polymers and supramolecular systems
    1. 3.1 Introduction
    2. 3.2 Basic principles of different synthetic materials
    3. 3.3 Materiomics using synthetic materials
    4. 3.4 Future perspectives
    5. 3.5 Snapshot summary
  11. Chapter 4 Microfabrication techniques in materiomics
    1. 4.1 Basic principles of microfabrication
    2. 4.2 The application of microfabrication in materiomics
    3. 4.3 Future perspectives
    4. 4.4 Snapshot summary
  12. Chapter 5 Bioassay development
    1. 5.1 Basic principles of assay development
    2. 5.2 Relation to materiomics
    3. 5.3 Future perspectives
    4. 5.4 Snapshot summary
  13. Chapter 6 High-content imaging
    1. 6.1 Origins of high-content imaging
    2. 6.2 High-content imaging techniques
    3. 6.3 The image analysis pipeline
    4. 6.4 Software
    5. 6.5 High-content imaging in materiomics
    6. 6.6 Future perspectives
    7. 6.7 Snapshot summary
  14. Chapter 7 Computational analysis of high-throughput material screens
    1. 7.1 Basic principles of data analysis
    2. 7.2 Computational analysis in materiomics research
    3. 7.3 Future perspectives
    4. 7.4 Snapshot summary
  15. Chapter 8 Upscaling of high-throughput material platforms in two and three dimensions
    1. 8.1 Basic upscaling principles
    2. 8.2 Upscaling and materiomics
    3. 8.3 Future perspectives
    4. 8.4 Snapshot summary
  16. Chapter 9 Development of materials for regenerative medicine: from clinical need to clinical application
    1. 9.1 Basic principles: development of materials for regenerative medicine
    2. 9.2 Relation to materiomics: from high-throughput screening to large animal studies and beyond
    3. 9.3 Future perspectives
    4. 9.4 Snapshot summary
  17. Chapter 10 Non-biomedical applications of materiomics
    1. 10.1 Tutorial on basic principles
    2. 10.2 Relation to materiomics
    3. 10.3 Future perspectives
    4. 10.4 Snapshot summary
  18. Chapter 11 Beyond bed and bench
  19. Index