A simple yet powerful GPO setting that is quite common to see in corporate environments is the removal of the Shut down and Restart functionality of Windows computers. This can be a critical thing inside an RDS or VDI environment, as you certainly wouldn't want users to have access to shut down a server that is hosting multiple people. Additionally, employees might be used to shutting down their home computers at night, but most companies roll out patches and updates overnight and so typically want their workstations to be turned on during those nights. If you had users shutting down their computers every night, their updates wouldn't install until the daytime hours and could interfere with their work.
In any case, ...
