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Hydroxyapatite by Yoshiki Oshida

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CHAPTER 9

SCAFFOLDS AND DRUG-DELIVERY SYSTEMS

Yoshiki Oshida and Masaki Fukai

9.1   INTRODUCTION

Tissue engineering has been defined as the application of scientific principles and clinical techniques to the design, construction, modification, and growth of living tissue using biomaterials, cells, and bioactive factors alone and in combination in order to restore and regenerate tissues using scaffolds, stem cells, growth factors, and gene therapy, and, for orthopedic surgery, it has evolved to meet a clinical need to develop suitable alternatives to current bone grafting techniques [1, 2]. It involves the use of osteoconductive biomaterial scaffolds, with osteogenic cell populations and osteoinductive bioactive factors. The three components for ...

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