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Handbook of Biofuels Production, 2nd Edition by James Clark, Karen Wilson, Carol Ki Lin, Rafael Luque

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8.3. The biochemistry of lipid accumulation in the oleaginous microorganisms

8.3.1. General remarks

When various sugars or similarly metabolized compounds (eg, glycerol, polysaccharides) are utilized for the production of SCO, accumulation of lipid in the microbial cells or mycelia (the so-called “de novo” lipid accumulation process) is triggered by exhaustion of nitrogen from the growth medium, which allows the conversion of sugar to storage lipid (Ratledge, 1988, 1994; Ratledge and Wynn, 2002; Wynn and Ratledge, 2006; Papanikolaou and Aggelis, 2009, 2011; Fakas et al., 2009b). In contrast, when growth is conducted on hydrophobic carbon sources (eg, fats, oils), accumulation of storage lipids (the so-called “ex novo” lipid accumulation process) ...

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