Color blindness is not the only reason to take the choice of colors in an interface seriously: there are other visual deficiencies, such as cataract and low vision, common in the elderly, which is in an increasing share of users; and even with normal view, the context affects how one perceives and sees the colors: brightness and contrast of the monitor, the lighting of the environment, and the time of day.
This becomes critical when a design is set on a Cinema Display and users have another type of monitor to access, regardless of their age and whether or not they have any type of visual impairment.
Of course, that gray text on a slightly lighter gray background looks stylish, but an ordinary computer monitor will not be ...
