Chapter 13

The Big ORF Theory

Algorithmic, Computational, and Approximation Approaches to Open Reading Frames in Short- and Medium-Length dsDNA Sequences

Steven M. Carr1,2,4 scarr@mun.ca; H. Dawn Marshall1; Todd Wareham2; Donald Craig3    1 Department of Biology, Memorial University of Newfoundland, St. John’s NL, Canada2 Department of Computer Science, Memorial University of Newfoundland, St. John’s NL, Canada3 eHealth Research Unit (Faculty of Medicine), Memorial University of Newfoundland, St. John’s NL, Canada4 Terra Nova Genomics, Inc., St. John’s NL, Canada

Abstract

In the genomic data-mining era of genetics and bioinformatics, a frequent task is the exploration of double-stranded DNA (dsDNA) sequence data for the occurrence of protein-coding ...

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