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Durability and Reliability of Medical Polymers by A Stamboulis, M Jenkins

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4

Understanding transport phenomena and degradation of bioresorbable medical polymers

F. Rossi and G. Perale,     Politecnico di Milano, Italy

Abstract:

The thermodynamic processes involved in degradation and drug release in resorbable polymeric drug loaded systems are explained in detail. To achieve a quantitative description of the thermodynamic movement to equilibrium in such systems presents some mathematical difficulties and the differing approaches are considered. The importance of irreversible thermodynamic processes is investigated by the analysis of phenomenological and kinetic mathematical approaches. The importance of mathematical models in investigating the transport phenomena that influence the design parameters and properties ...

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