You are previewing Durability and Reliability of Medical Polymers.
O'Reilly logo
Durability and Reliability of Medical Polymers

Book Description

Given the widespread use of polymers in medical devices, the durability and reliability of this material in use is an area of critical importance. Durability and reliability of medical polymers reviews the performance of both bioresorbable and non-bioresorbable medical polymers.

Part one provides a review of the types and properties of bioresorbable medical polymers. The effect of molecular structure on properties is discussed, along with the processing of bioresorbable and other polymers for medical applications. Transport phenomena and the degradation of bioresorbable medical polymers are reviewed, before an exploration of synthetic bioresorbable polymers and their use in orthopaedic tissue regeneration. Part two goes on to explore the durability and reliability of non-bioresorbable medical polymers, and wear processes in polymer implants and ageing processes of biomedical polymers in the body are discussed in depth, before an investigation into manufacturing defects and the failure of synthetic polymeric medical devices.

With its distinguished editors and international team of expert contributors, Durability and reliability of medical polymers is an essential tool for all materials scientists, researchers and engineers involved in the design, development and application of medical polymers, whilst also providing a helpful overview of the subject for biologists, chemist and clinicians.

  • Comprehensively examines the performance of both bioresorbable and non-bioresorbable medical polymers
  • Discusses the processing of bioresorbable and other polymers for medical applications, before reviewing the degradation of bioresorbable medical polymers
  • Explores the durability and reliability of non-bioresorbable medical polymers and discusses wear processes in polymer implants and ageing processes of biomedical polymers in the body

Table of Contents

  1. Cover image
  2. Title page
  3. Table of Contents
  4. Copyright
  5. Contributor contact details
  6. Woodhead Publishing Series in Biomaterials
  7. Part I: Types and properties of bioresorbable medicalpolymers
    1. Chapter 1: Types of bioresorbable polymers for medical applications
      1. Abstract:
      2. 1.1 Introduction
      3. 1.2 Aliphatic polyesters
      4. 1.3 Polyanhydrides
      5. 1.4 Poly(ortho esters)
      6. 1.5 Polyphosphazenes
      7. 1.6 Poly(amino acids) and ‘pseudo’ poly(amino acids)
      8. 1.7 Polyalkylcyanoacrylates
      9. 1.8 Poly(propylene fumarate) (PPF), poloxamers, poly(p-dioxanone) (PPDO), polyvinyl alcohol (PVA)
    2. Chapter 2: The effect of molecular structure on the properties of biomedical polymers
      1. Abstract:
      2. 2.1 Introduction: the molecular structure of polymers
      3. 2.2 Molecular weight and polymer properties
      4. 2.3 Macromolecular conformation, crystallisation and polymer properties
      5. 2.4 The effect of the amorphous state and glass transition temperature on polymer properties
      6. 2.5 Biphasic systems: linear crystalline polymers and their properties
    3. Chapter 3: Processing of bioresorbable and other polymers for medical applications
      1. Abstract:
      2. 3.1 Introduction
      3. 3.2 Extrusion
      4. 3.3 Mixing processes
      5. 3.4 Molding processes
      6. 3.5 Secondary shaping
      7. 3.6 Calendering
      8. 3.7 Coating
      9. 3.8 Foaming
      10. 3.9 Solvent casting
      11. 3.10 Challenges in biopolymer processing
      12. 3.11 Conclusions
    4. Chapter 4: Understanding transport phenomena and degradation of bioresorbable medical polymers
      1. Abstract:
      2. 4.1 Introduction to transport phenomena in irreversible processes
      3. 4.2 Introduction to mathematical modelling
      4. 4.3 Conclusions and future trends
    5. Chapter 5: Synthetic bioresorbable polymers
      1. Abstract:
      2. 5.1 Introduction
      3. 5.2 Bioresorbable polymers
      4. 5.3 Degradation of aliphatic polyesters
      5. 5.4 Factors affecting aliphatic polymer degradation
      6. 5.5 Processing and devices
      7. 5.6 Conclusions
    6. Chapter 6: Using synthetic bioresorbable polymers for orthopedic tissue regeneration
      1. Abstract:
      2. 6.1 Introduction
      3. 6.2 Poly (α-hydroxy acids)
      4. 6.3 Polylactones
      5. 6.4 Polyanhydrides
      6. 6.5 Fumarate-based polymers
      7. 6.6 Hydrogels
      8. 6.7 Future trends
      9. 6.8 Conclusions
  8. Part II: Aspects of durability and reliability of non-bioresorbable medical polymers
    1. Chapter 7: Wear processes in polymer implants
      1. Abstract:
      2. 7.1 Introduction
      3. 7.2 Implants
      4. 7.3 Wear processes and theory for polymer implants
      5. 7.4 Polymers
      6. 7.5 Wear debris in the body
      7. 7.6 Future trends
      8. 7.7 Sources of further information and advice
    2. Chapter 8: Ageing processes of biomedical polymers in the body
      1. Abstract:
      2. 8.1 Introduction
      3. 8.2 Principles of chemical and biochemical degradation and calcification
      4. 8.3 Effect of natural ageing of medical polymers
      5. 8.4 Principles of accelerated ageing
      6. 8.5 Conclusions and summary
      7. 8.6 Sources of further information and advice
      8. 8.7 Acknowledgements
    3. Chapter 9: The failure of synthetic polymeric medical devices
      1. Abstract:
      2. 9.1 Introduction
      3. 9.2 Forensic methods
      4. 9.3 Catheter failure
      5. 9.4 Balloon catheters and angioplasty
      6. 9.5 Breast implants
      7. 9.6 Intraocular lenses
      8. 9.7 Failure of Foley catheters
      9. 9.8 Sutures
      10. 9.9 Conclusions
      11. 9.10 Acknowledgements
    4. Chapter 10: Manufacturing defects in polymeric medical devices
      1. Abstract:
      2. 10.1 Introduction
      3. 10.2 Polymer moulding
      4. 10.3 Catheter systems
      5. 10.4 Security cap for gas cylinders
      6. 10.5 Breathing tube failures
      7. 10.6 A failed crutch
      8. 10.7 Cracked medical tubing
      9. 10.8 Conclusions
      10. 10.9 Acknowledgements
  9. Index