Biomaterials for TE/RM products
Abstract
Biomaterials may be required to support the cellular active biological ingredient within the context of a TE/RM product. In this chapter, we briefly review the principal classes of natural and synthetic biomaterials commonly used within the TE/RM industry. We illustrate the selection criteria for identification of appropriate biomaterial candidates for TE/RM product application using ‘real world’ examples from Tengion’s ongoing development of Neo-Kidney Augment™ and Neo-Bladder Augment™ and Neo-Gastrointestinal tract (Neo-GI™) regeneration programs.
Keywords
biomaterials
extracellular matrix
decell/recell
hydrogel
chronic kidney disease
gelatin
poly-caprolactone
poly-glycolic acid
poly-lactic-co ...
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