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Developments in Tissue Engineered and Regenerative Medicine Products by J Ludlow, J Basu

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1

Overview of tissue engineering/regenerative medicine

1.1 Introduction

Tissue engineering/regenerative medicine (TE/RM) refers to a broad range of emerging technologies that employ cells, biomaterials or cell/biomaterial combinations (referred to as ‘constructs’) to reconstitute functional tissue or organ-like structures ex vivo (neo-organs) and/or to catalyze organogenesis de novo by utilizing the body’s innate ability to regenerate itself. Emerging approaches to TE/RM encompass the full spectrum of cells, biomaterials and cell/biomaterial combinations. However, from a biotechnology perspective, perhaps the most significant recent developments in TE/RM product development include:

• Approval by the Food and Drug Administration (FDA) for ...

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