Computer-Aided Applications in Pharmaceutical Technology

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Experimental design application and interpretation in pharmaceutical technology

Jelena Djuris, Svetlana Ibric and Zorica Djuric,     Department of Pharmaceutical Technology and Cosmetology, Faculty of Pharmacy, University of Belgrade

Abstract:

This chapter provides a basic theoretical background on experimental design application and interpretation. Techniques described include screening designs, full and fractional factorial designs, Plackett–Burman design, D-optimal designs, response surface methodology, central composite designs, Box–Behnken design, and mixture designs, etc. The reader will be introduced to the experimental domains covered by specific design, making it easier to select the one appropriate for the problem. After theoretical ...