L.K. Von Segesser, Centre Hospitalier Universitaire Vaudois, Switzerland
This chapter reviews surface modifying coatings for extracorporeal circuits such as cardiopulmonary bypass, mechanical circulatory support, right- and left-ventricular assist devices, left heart bypass, and shunts. Surface modifying coatings reviewed for the experimental setting and clinical applications include heparin surface coating, end-point attached heparin, biomembrane mimicry, polymeric phospholipids, and phosphorylcholine. The main findings for the various applications and surface modifications are described, referenced, and illustrated.