NAT Design Considerations
While NAT has done much to extend the life of IPv4, it does have limitations you should consider in your design. Consider the following:
Applications requiring end-to-end connectivity, where source and destination IP addresses are not modified at any point on the data path, could fail because of NAT’s modification of source and destination IP addresses.
NAT might have compatibility issues with IPsec, because IPsec performs message integrity checks, which could fail because of NAT’s manipulation of header contents.
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