Categorical Data Analysis Using SAS, Third Edition, 3rd Edition

Chapter 11

Quantal Response Data Analysis

Contents

11.1   Introduction

11.2   Estimating Tolerance Distributions

11.2.1   Analyzing the Bacterial Challenge Data

11.3   Comparing Two Drugs

11.3.1   Analysis of the Peptide Data

11.4   Analysis of Pain Study

11.5   Estimating Tolerance Distributions

Appendix A: SAS/IML Macro for Confidence Intervals of Ratios Using Fieller's Theorem

11.1 Introduction

Quantal response data analysis deals with subject response to a stimulus that occurs with greater and greater intensity. This covers a great deal of territory, from the evaluation of drugs at various dosages to the assessment of radiation impact to the study of growth and development in children. Often, the reagent is a new drug and the subjects ...