11.4. Analysis of Pain Study
Researchers investigated a new drug for pain relief by studying its effect on groups of subjects with two different diagnoses. The drug was administered at five dosages, and the outcome measured was whether the subjects reported adverse effects. Table 11.4 contains the data. Interest lies in investigating the association of adverse effects with dose and diagnosis; in addition, there is interest in describing the influence of dose and diagnosis on whether there are adverse effects with a statistical model.
| Diagnosis I | Diagnosis II | |||
|---|---|---|---|---|
| Dose | Adverse | Not | Adverse | Not |
| 1 | 3 | 26 | 6 | 26 |
| 5 | 7 | 26 | 20 | 12 |
| 10 | 10 | 22 | 26 | 6 |
| 12 | 14 | 18 | 28 | 4 |
| 15 | 18 | 14 | 31 | 1 |
Unlike the previous bioassay analysis, this study does not compare the tolerance distributions of ...
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