2.7. McNemar’s Test
The 2 × 2 table often contains information collected from matched pairs, experimental units for which two related responses are made. The sampling unit is no longer one individual but a pair of related individuals, which could be two locations on the same individual or two occasions for the same individual. For example, in case-control studies, cases are often matched to controls on the basis of demographic characteristics; interest lies in determining whether there is a difference between control exposure to a risk factor and case exposure to the same risk factor. Other examples of matched pairs are left eye and right eye measurements, and husband and wife voting preferences. Measurements at two different time points can ...
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