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Biomedical Imaging

Book Description

The development of imaging techniques is of great importance for the diagnosis of disease, monitoring of medical implants and for strategies for personalised medicine. Significant advances are being made in this technology and Biomedical imaging discusses the technologies and latest developments in this increasingly important field.

Chapters in part one explore the full scale of imaging technologies from Atomic Force Microscopy (AFM) to Positron Emission Tomography (PET), as well as the Next Generation techniques that could provide the basis for personalised medicine. Part two highlights application specific biomedical imaging methods, including ophthalmic imaging of ocular circulation, imaging methods for detection of joint degeneration, neural brain activation imaging and the use of brain imaging to assess post therapy responses. Further chapters review intravascular, cardiovascular and whole body magnetic resonance imaging (MRI).

Biomedical imaging is a technical resource for those concerned with imaging and diagnosis including materials scientists and engineers as well as clinicians and academics.

  • Explores the full scale of imaging technologies from Atomic Force Microscopy (AFM) to Positron Emission Tomography (PET), as well as the Next Generation techniques that could provide the basis for personalised medicine
  • Highlights application specific biomedical imaging methods, including ophthalmic imaging of ocular circulation, imaging methods for detection of joint degeneration, neural brain activation imaging and the use of brain imaging to assess post therapy responses
  • Reviews intravascular, cardiovascular and whole body magnetic resonance imaging (MRI)

Table of Contents

  1. Cover image
  2. Title page
  3. Table of Contents
  4. Copyright
  5. Contributor contact details
  6. Woodhead Publishing Series in Biomaterials
  7. Foreword
  8. Preface
  9. Part I: Imaging technologies
    1. 1. Biomedical Positron Emission Tomography (PET) imaging
      1. Abstract:
      2. 1.1 Introduction
      3. 1.2 The role of PET in oncology
      4. 1.3 Individual oncological PET tracers and their applications
      5. 1.4 The role of PET in neurology
      6. 1.5 The role of PET in cardiology
      7. 1.6 The role of PET in drug development
      8. 1.7 Conclusion and future trends
      9. 1.8 References
    2. 2. Atomic Force Microscopy (AFM) in biomedical research
      1. Abstract:
      2. 2.1 Introduction
      3. 2.2 Key concepts of atomic force microscopy (AFM)
      4. 2.3 AFM imaging methodologies
      5. 2.4 AFM nano-indentation
      6. 2.5 Specialized techniques
      7. 2.6 Conclusion and future trends
      8. 2.7 Bibliography
    3. 3. Next generation techniques for biomedical imaging
      1. Abstract:
      2. 3.1 Introduction
      3. 3.2 An overview of imaging sciences
      4. 3.3 New developments to improve diagnosis and biological analysis
      5. 3.4 Imaging techniques: imaging Omics and array imaging
      6. 3.5 Plasmonics
      7. 3.6 iBIOS Omics imaging: instrument assembly
      8. 3.7 Label-free measurements: problems of nonspecific binding and the analyte dynamic range
      9. 3.8 Data correction and analysis
      10. 3.9 Biomarker panel analysis
      11. 3.10 Future trends in Omics imaging
      12. 3.11 Conclusion
      13. 3.12 Sources of further information and advice
      14. 3.13 Acknowledgement
      15. 3.14 References
  10. Part II: Application-specific biomedical imaging techniques
    1. 4. Brain imaging: assessing therapy responses using quantitative imaging biomarkers
      1. Abstract:
      2. 4.1 Introduction
      3. 4.2 Epidemiology and classification of brain tumors
      4. 4.3 Treatment
      5. 4.4 The role of neuroimaging: computed tomography (CT) and magnetic resonance (MR)
      6. 4.5 The role of neuroimaging: PET and tracers
      7. 4.6 Conclusion
      8. 4.7 Acknowledgements
      9. 4.8 References
    2. 5. Neural brain activation imaging
      1. Abstract:
      2. 5.1 Introduction
      3. 5.2 Functional magnetic resonance imaging (fMRI)
      4. 5.3 Multimodal imaging
      5. 5.4 13C magnetic resonance spectroscopy (MRS)
      6. 5.5 Sources of further information and advice
      7. 5.6 References
    3. 6. Ophthalmic imaging of ocular circulation for detecting disease
      1. Abstract:
      2. 6.1 Introduction: assessment of ocular blood flow
      3. 6.2 Assessing blood flow using Doppler imaging and scanning laser ophthalmoscope
      4. 6.3 Further methods for assessing ocular blood flow
      5. 6.4 Recent and emerging techniques for assessing ocular blood flow
      6. 6.5 Association of ocular blood flow with ophthalmic disease
      7. 6.6 Conclusion
      8. 6.7 References
    4. 7. Intravascular magnetic resonance imaging (MRI)
      1. Abstract:
      2. 7.1 Introduction
      3. 7.2 Intravascular magnetic resonance (MR) operations
      4. 7.3 Catheter visualization
      5. 7.4 Tracking using intravascular MR coils
      6. 7.5 Signal-to-noise ratio (SNR) performance of catheter coils
      7. 7.6 Safety of intravascular catheters
      8. 7.7 Conclusion
      9. 7.8 References
    5. 8. Cardiovascular magnetic resonance imaging (MRI)
      1. Abstract:
      2. 8.1 Introduction
      3. 8.2 Biology of atherosclerosis
      4. 8.3 Principles of cardiovascular magnetic resonance (MR) imaging
      5. 8.4 Preclinical molecular imaging in atherosclerosis
      6. 8.5 Clinical imaging of atherosclerosis
      7. 8.6 Conclusion and future trends
      8. 8.7 References
    6. 9. Imaging methods for detection of joint degeneration
      1. Abstract:
      2. 9.1 Introduction
      3. 9.2 An overview of osteoarthritis
      4. 9.3 Magnetic resonance imaging (MRI)
      5. 9.4 Computer tomography (CT) based imaging
      6. 9.5 Ultrasound imaging for cartilage
      7. 9.6 Vascular imaging
      8. 9.7 Other imaging modalities
      9. 9.8 Conclusion
      10. 9.9 References
    7. 10. Whole body magnetic resonance imaging (MRI)
      1. Abstract:
      2. 10.1 Introduction
      3. 10.2 Gastrointestinal (GI) magnetic resonance imaging (MRI)
      4. 10.3 Liver imaging
      5. 10.4 Kidney imaging
      6. 10.5 Foetal and placental imaging
      7. 10.6 Conclusion
      8. 10.7 Sources of further information and advice
      9. 10.8 References
  11. Index