Chapter 4. Population Genetics
In this chapter, we will cover the following recipes:
- Managing datasets with PLINK
- Introducing the Genepop format
- Exploring a dataset with Bio.PopGen
- Computing F-statistics
- Performing Principal Components Analysis
- Investigating population structure with Admixture
Introduction
Population genetics is the study of changes of frequency of alleles in a population on the basis of selection, drift, mutation, and migration. The previous chapters focused mainly on data processing and cleanup; this is the first chapter in which we will actually infer interesting biological results.
There is a lot of interesting population genetics analysis based on sequence data, but as we already have quite a few recipes to deal with sequence data, ...
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