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Biodesign by Paul Yock, Josh Makower, Stefanos Zenios

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3.2 Concept Screening

Introduction
A “leap of faith” is defined as an act or instance of accepting or trusting in something that cannot readily be seen or proved.1 Innovators are required to choose a handful of solution concepts to pursue from among the hundreds of ideas coming out of one or more brainstorming sessions, with little or no detailed information about each solution’s ability to satisfy the criteria laid out in the need specification. To this extent, concept screening is a leap of faith. Is the solution technically feasible? Is enough understood about the mechanisms of the disease or critical interactions between different engineering concepts to make the solution viable? How much time, effort, and money will it take to determine ...

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