The Importance of (Sub)sequence Comparison in Molecular Biology
Sequence comparison, particularly when combined with the systematic collection, curration, and search of databases containing biomolecular sequences, has become essential in modern molecular biology. Commenting on the (then) near-completion of the effort to sequence the entire yeast genome (now finished), Stephen Oliver says
In a short time it will be hard to realize how we managed without the sequence data. Biology will never be the same again. 
One fact explains the importance of molecular sequence data and sequence comparison in biology.
The first fact of biological sequence ...