Book description
An in-depth look at the latest research, methods, and applications in the field of protein bioinformatics
This book presents the latest developments in protein bioinformatics, introducing for the first time cutting-edge research results alongside novel algorithmic and AI methods for the analysis of protein data. In one complete, self-contained volume, Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics addresses key challenges facing both computer scientists and biologists, arming readers with tools and techniques for analyzing and interpreting protein data and solving a variety of biological problems.
Featuring a collection of authoritative articles by leaders in the field, this work focuses on the analysis of protein sequences, structures, and interaction networks using both traditional algorithms and AI methods. It also examines, in great detail, data preparation, simulation, experiments, evaluation methods, and applications. Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics:
Highlights protein analysis applications such as protein-related drug activity comparison
Incorporates salient case studies illustrating how to apply the methods outlined in the book
Tackles the complex relationship between proteins from a systems biology point of view
Relates the topic to other emerging technologies such as data mining and visualization
Includes many tables and illustrations demonstrating concepts and performance figures
Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics is an essential reference for bioinformatics specialists in research and industry, and for anyone wishing to better understand the rich field of protein bioinformatics.
Table of contents
- Cover
- Series
- Title Page
- Copyright
- Preface
- Contributors
-
Part I: From Protein Sequence to Structure
- Chapter 1: Emphasizing The Role of Proteins in Construction of the Developmental Genetic Toolkit in Plants
- Chapter 2: Protein Sequence Motif Information Discovery
- Chapter 3: Identifying Calcium Binding Sites in Proteins
- Chapter 4: Review of Imbalanced Data Learning for Protein Methylation Prediction
- Chapter 5: Analysis and Prediction of Protein Posttranslational Modification Sites
-
Part II: Protein Analysis and Prediction
- Chapter 6: Protein Local Structure Prediction
- Chapter 7: Protein Structural Boundary Prediction
- Chapter 8: Prediction of RNA Binding Sites in Proteins
- Chapter 9: Algorithmic Frameworks for Protein Disulfide Connectivity Determination
- Chapter 10: Protein Contact Order Prediction: Update
- Chapter 11: Progress in Prediction of Oxidation States of Cysteines via Computational Approaches
- Chapter 12: Computational Methods in CryoElectron Microscopy 3D Structure Reconstruction
-
Part III: Protein Structure Alignment and Assessment
- Chapter 13: Fundamentals of Protein Structure Alignment
- Chapter 14: Discovering 3D Protein Structures for Optimal Structure Alignment
- Chapter 15: Algorithmic Methodologies for Discovery of Nonsequential Protein Structure Similarities
- Chapter 16: Fractal Related Methods for Predicting Protein Structure Classes and Functions
- Chapter 17: Protein Tertiary Model Assessment
-
Part IV: Protein–Protein Analysis of Biological Networks
- Chapter 18: Network Algorithms For Protein Interactions
-
Chapter 19: Identifying Protein Complexes from Protein–Protein Interaction Networks
- 19.1 Introduction
- 19.2 Density-Based and Local Search Methods
- 19.3 Hierarchical Clustering Methods
- 19.4 Finding Overlapping Clusters
- 19.5 Identification of Protein Complexes by Integrating Multiple Biological Sources
- 19.6 Identifying Protein Complexes From Dynamic PPI Network
- 19.7 Challenges and Future Research
- References
- Chapter 20: Protein Functional Module Analysis With Protein–Protein Interaction (PPI) Networks
- Chapter 21: Efficient Alignments of Metabolic Networks with Bounded Treewidth
- Chapter 22: Protein–protein Interaction Network Alignment: Algorithms and Tools
-
Part V: Application of Protein Bioinformatics
- Chapter 23: Protein-Related Drug Activity Comparison Using Support Vector Machines
- Chapter 24: Finding repetitions in biological networks: challenges, trends, and applications
- Chapter 25: MeTaDoR: Online Resource and Prediction Server for Membrane Targeting Peripheral Proteins
- Chapter 26: Biological networks–based analysis of gene expression signatures*
- Index
- Series
Product information
- Title: Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics
- Author(s):
- Release date: November 2013
- Publisher(s): Wiley-IEEE Press
- ISBN: 9781118345788
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