By the end of this chapter you should be familiar with
- Representation of three dimensional molecules in two dimensions.
- The hybridization of carbon in alkanes, alkenes and alkynes.
- Chair and boat conformations, ring inversion and 1,3-diaxial interactions in cyclohexanes.
- Chirality, Fischer, Newman and saw-horse projections, R/S, erythro/threo and syn/anti configuration, meso configuration, enantiomers and diastereoisomers, racemization and resolution.
Vladimir Prelog performed wide-ranging research on the stereochemistry of alkaloids, antibiotics, enzymes and other natural compounds. In particular, he contributed to the understanding of stereoisomerism, in which two compounds of identical ...