Free Radical Reactions
By the end of this chapter you should be familiar with
- Evidence for the existence of radicals, their detection and characterization.
- Structure and bonding of radicals. Radical reactions follow different rules to those of ionic reactions.
- Generation, stability and reactions of free-radicals. Radicals favour conjugate addition.
- Stereochemistry of radical substitution reactions.
- Cyclization is easy with radical reactions.
A carbon-centered radical is a structure having an unpaired electron on a carbon atom and a formal charge of zero. Thus, a free radical is an atom or a group of atoms with an unpaired electron. (This definition includes certain stable, inorganic molecules and atoms ...