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23rd European Symposium on Computer Aided Process Engineering by Ilkka Turunen, Andrzej Kraslawski

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Improving Lead Time of Sterile Drug Product Manufacturing Using Monte Carlo Simulation

Lukas Eberle, a, b, Hirokazu Sugiyamaa, c and Rainer Schmidta,    aF. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, 4070 Basel, Switzerland, bETH Zuerich, Wolfgang-Pauli-Strasse 10, 8093 Zuerich, Switzerland, cThe University of Tokyo, 7–3–1, Hongo, Bunkyo-ku, 113–8656 Tokyo, Japan, lukas.eberle@chem.ethz.ch

Abstract

Reliable product supply is one of the most critical missions of the pharmaceutical industry. The lead time, i.e. the duration between start and end of an activity, needs to be managed in any production facility in order to make scheduling predictable’ agile and flexible. We present a method for measuring and improving production lead time of ...

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