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23rd European Symposium on Computer Aided Process Engineering by Ilkka Turunen, Andrzej Kraslawski

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An Integrated Computational Model of Powder Release, Dispersion, Breakage, and Deposition in a Dry Powder Inhaler

A.H. Alexopoulosb, J Milenkovica, b and C Kiparissidesa, b,    aDepartment of Chemical Engineering, Aristotle University of Thessaloniki, P.O. Box 472, 54124, Thessaloniki, Greece, bChemical Process & Energy Resources Institute/ Centre for Research and Technology Hellas, Greece

Abstract

The present work describes an integrated computational model of airflow as well as particle dispersion, breakage and deposition in a Dry Powder Inhaler, DPI. The integrated model combines computational fluid dynamics, CFD, an Eulerian/Lagrangian model for particle motion and deposition, and a particle-wall collision model, which are employed to determine ...

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